Pressor Effects of Norepinephrine After Drastic Reduction of Sodium Intake

Pressor Effects of Norepinephrine After Drastic Reduction of Sodium Intake

The mechanisms wh(eeby, dietary sodium restriction leads to decreased arterial blood pressure is obscure. Previously reported studies of patients with arterial hypertension showed a lessened pressor response to norepinephrine after sodium restriction. In the present investigations, reduction in pressor response to norepinephrine during the low sodium period was observed only occasionally; sodiu...

Pressor effects of norepinephrine after drastic reduction of sodium intake.

The mechanisms wh(eeby, dietary sodium restriction leads to decreased arterial blood pressure is obscure. Previously reported studies of patients with arterial hypertension showed a lessened pressor response to norepinephrine after sodium restriction. In the present investigations, reduction in pressor response to norepinephrine during the low sodium period was observed only occasionally; sodiu...

Sodium intake alters the effects of norepinephrine on blood pressure.

To examine the interactions between sodium balance and the sympathetic nervous system, we studied eight normotensive men after high (800 mEq/day) and low (10 mEq/day) sodium intake. We measured blood pressure (BP), arterial, venous, and urinary norepinephrine (NE) before and during incremental infusion of NE. We found significant direct, linear relationships (p less than 0.001) between the dose...

Pressor effects of epinephrine, norepinephrine and desoxycorticosterone acetate weakened by sodium withdrawal.

Plasma norepinephrine variations with dietary sodium intake.

Plasma catecholamine and renin activity levels were measured across a range of dietary sodium intakes (10--300 mEq/day) in 20 normal male volunteers. Supine plasma norepinephrine levels presented a triphasic pattern in relation to urine sodium, whereas epinephrine levels were not significantly altered by sodium intake, and renin showed the well-known hyperbolic relationship to urine sodium excr...